Breast Cancer
Overview
Breast cancer is a cancer that starts in the tissues of the breast.There are two main types of breast cancer:Ductal carcinoma starts in the tubes (ducts) that move milk from the breast to the nipple. Most breast cancers are of this type.Lobular carcinoma starts the lobules, the parts of the breast that produce milk.In rare cases, breast cancer can start in other areas of the breast.
Symptoms and Types
Over the course of a lifetime, 1 in 8 women will be diagnosed with breast cancer.
Risk factors you cannot change include:
Age and gender -- Your risk of developing breast cancer increases as you get older. The majority of advanced breast cancer cases are found in women over age 50. Women are 100 times more likely to get breast cancer than men.
Family history of breast cancer -- You may also have a higher risk for breast cancer if you have a close relative has had breast, uterine, ovarian, or colon cancer. About 20 - 30% of women with breast cancer have a family history of the disease.
Genes -- Some people have genes that make them more prone to developing breast cancer.Menstrual cycle -- Women who get their periods early (before age 12) or went through menopause late (after age 55) have an increased risk for breast cancer.
Other risk factors include:
Alcohol use -- Drinking more than 1 - 2 glasses of alcohol a day may increase your risk for breast cancer.
Childbirth -- Women who have never had children or who had them only after age 30 have an increased risk for breast cancer. Being pregnant more than once or becoming pregnant at an early age reduces your risk of breast cancer.
DES -- Women who took diethylstilbestrol (DES) to prevent miscarriage may have an increased risk of breast cancer after age 40. This drug was given to the women in the 1940s - 1960s.
Hormone replacement therapy (HRT) -- You have a higher risk for breast cancer if you have received hormone replacement therapy for several years or more. Many women take HRT to reduce the symptoms of menopause.
Obesity -- Obesity has been linked to breast cancer, although this link is controversial. The theory is that obese women produce more estrogen, which can fuel the development of breast cancer.
Radiation -- If you received radiation therapy as a child or young adult to treat cancer of the chest area, you have a significantly higher risk for developing breast cancer. The younger you started such radiation, the higher your risk -- especially if the radiation was given when a female was developing breasts.
Diagnosis
Early breast cancer usually does not cause symptoms. This is why regular breast exams are important.
As the cancer grows, symptoms may include:
Breast lump or lump in the armpit that is hard, has uneven edges, and usually does not hurt
Change in the size, shape, or feel of the breast or nipple -- for example, you may have redness, dimpling, or puckering that looks like the skin of an orange
Fluid coming from the nipple -- may be bloody, clear-to-yellow, or green, and look like pus
Men get breast cancer, too. Symptoms include breast lump and breast pain and tenderness. Symptoms of advanced breast cancer may include:
Bone pain
Breast pain or discomfort
Skin ulcers
Swelling of one arm (next to breast with cancer)
Weight loss
Mammography is the most effective way of detecting breast cancer early.
Contact your physician if:
You have a breast or armpit lump
You are a woman age 40 or older and have not had a mammogram in the last year
You are a woman age 35 or older and have a mother or sister with breast cancer, or have already had cancer of the breast, uterus, ovary, or colon.
You do not know how or need help learning how to perform a breast self-examination
Treatment and Care
Treatment is based on many factors, including type and stage of the breast cancer, whether the cancer is sensitive to certain hormones, and whether or not the cancer overproduces (over expresses) a gene called HER2/neu.
In general, cancer treatments may include:
Chemotherapy medicines to kill cancer cells
Radiation therapy to destroy cancerous tissue
Surgery to remove cancerous tissue -- a lumpectomy removes the breast lump; mastectomy removes all or part of the breast and possible nearby structures
Hormonal therapy to block certain hormones that fuel cancer growth
Targeted therapy to interfere with cancer cell grow and functionMost women receive a combination of treatments.
New, improved treatments are helping persons with breast cancer live longer than ever before. However, even with treatment, breast cancer can spread to other parts of the body. Sometimes, cancer returns even after the entire tumor is removed and nearby lymph nodes are found to be cancer-free.You may experience side effects or complications from cancer treatment. For example, radiation therapy may cause temporary swelling of the breast, and aches and pains around the area. Ask your doctor about the side effects you may have during treatment.